IN the film, "The 50 First Dates", Drew Barrymore plays a woman who suffers short-term memory loss, and doesn't remember that Adam Sandler is her boyfriend. She doesn't even remember meeting him at all. This doesn't deter Sandler, as Henry Roth, tries to win Barrymore's character, Lucy Whitmore, every day.
It was a funny premise, which apparently has basis in fact. In the New York Times today, is a piece on Henry Gustav Molaison, who was diagnosed with "profound amnesia" or the inability to form new memories, who passed away on December 2. Read about H.M..